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Nicotinamide Riboside (NR) - The Optimal NAD+ Precursor
Why is Nicotinamide Riboside (NR) superior to Niacin and Nicotinamide? The key lies in NR's exceptional efficiency in converting into NAD+, the crucial coenzyme for cellular processes.
NR utilizes a unique "NAD+ salvage pathway" for NAD+ synthesis. In this pathway, NR is efficiently converted into nicotinamide mononucleotide (NMN) by the enzyme nicotinamide riboside kinase (NRK). NMN is then swiftly transformed into NAD+ by the enzyme NMN adenylyltransferase (NMNAT). This streamlined process allows NR to bypass several rate-limiting steps, making it a more effective NAD+ precursor.
Compared to other forms of vitamin B3, NR is more readily and efficiently converted into NMN by NRK. This enzymatic step is a key factor in NR's superior ability to raise NAD+ levels.
Niacin, another form of vitamin B3, can be converted into NAD+ but often causes the undesirable "niacin flush" - a temporary reddening and warming of the skin. In contrast, NR does not induce this side effect, making it a more tolerable option for NAD+ supplementation.
Nicotinamide (NAM), the third form of vitamin B3, can also be converted into NAD+. However, this conversion results in the production of methyl nicotinamide (MeNAM), a byproduct that inhibits the crucial enzyme Sirtuin 1 (SIRT1), which plays a vital role in cellular metabolism and aging processes. NR, on the other hand, does not produce MeNAM during its conversion to NAD+, allowing for a more efficient utilization of NAD+ for cellular functions.
Probase Nutrition's NR supplements stand out as the superior choice. Each capsule contains 500mg of the purest and highest-quality NR, providing superior absorption and bioavailability. Probase Nutrition NR is the most efficient and safest way to elevate your NAD+ levels, supporting your cellular health and overall well-being.
By supplementing with Probase Nutrition's NR, you can expect enhanced cellular energy, slowed aging, and improved brain function. NR increases NAD+ levels, which activate sirtuins to support a longer lifespan and reduced risk of age-related diseases. NR has also been shown to enhance mitochondrial function, leading to increased mental clarity, better memory, and reduced fatigue.
Probase Nutrition's NR supplements are free from artificial colors, flavors, and preservatives, making them gluten-free, non-GMO, and vegan-friendly. These high-quality supplements can help individuals perform at their best every day by supporting brain health and reducing fatigue naturally.
In summary, Probase Nutrition's Nicotinamide Riboside (NR) supplements stand out as the optimal choice for supporting cellular energy, slowing aging, and enhancing brain function. Experience the benefits of increased NAD+ levels with this superior form of vitamin B3.
product information:
Attribute | Value | ||||
---|---|---|---|---|---|
product_dimensions | ‎3 x 2 x 2 inches; 1.41 ounces | ||||
date_first_available | ‎April 20, 2023 | ||||
manufacturer | ‎Probase Nutrition | ||||
best_sellers_rank | #74,564 in Health & Household (See Top 100 in Health & Household) #3,667 in Blended Vitamin & Mineral Supplements | ||||
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